Rewind Time.
Reveal Younger Skin.
Named “one of the biggest breakthroughs in skin care”, DefenAge™’s exclusive ingredient, Age-Repair Defensins™, work via a natural mechanism of action with your body’s stem cells to create beautiful skin. The initial results may become visible within one week of use. The technology is patent-pending, exclusively available in DefenAge™ and can be combined with almost any skin care regiment.
Inspired by the recent discovery of the skin’s regeneration process, the scientists at DefenAge™ have identified how to unlock the key to youth with powerful peptides called Age-Repair Defensins™. Paradigm-shifting DefenAge™ is the FIRST and ONLY 4th generation skin care featuring this stand-alone breakthrough NATURAL mechanism of action.
DefenAge™ is pioneering the future of skin care!
DefenAge™ Frequently Asked Questions
* Based on results obtained from a six-week clinical study of participants aged 48-68 using 2-Minute Reveal Masque one-to-two times a week and 24/7 Barrier Repair Cream and 8-in-1 BioSerum twice daily. Results were measured using QuantifiCare™ Clinical Imaging System. Individual results may vary.
We do use one ingredient derived from an invertebrate. Sea whip is a Caribbean coral believed to be the strongest anti-inflammatory to come from the sea. Only the ‘skeletal’ portion of the sea whip is collected by harvesters, who leave the live animal unharmed and available to multiply. No known disease or infection source is transferrable from the coral to humans.
Since the 24/7 Barrier Repair Cream contains a small amount of fragrance we do not recommend you apply it around your eyes. However, you can apply 8-in-1 BioSerum above and below your eyes.
It is under development in our laboratory. In the meantime, please be sure to apply the 8-in-1 BioSerum above and below your eyes as directed.

To our knowledge, none of these ingredients, either alone or in combination, totally relieves the appearance of age spots.
The DefenAge 24/7 Barrier Repair Cream and 8-in-1 BioSerum incorporate a revolutionary skin brightening technology, led by our patent-pending Age Repair Defensins™ to target skin discolorations at the source. When used in conjunction with the 2-Minute Reveal Masque twice weekly, residual unevenness and dead surface cells are lifted away. Within a week, the skin looks visibly brighter and skin discoloration is less apparent.
- Hydroquinone [CAS 123-31-9] Supporting Information for Toxicological Evaluation by the National Toxicology Program, 21 May 2009
- SCCS (Scientific Committee on Consumer Safety), Opinion on kojic acid, 26-27 June 2012
- International Agency for Research on Cancer, Monographs Volume 79, 2001
All products made by DefenAge Cosmeceuticals are tested on humans, not other animals. We do not believe animal studies are accurate enough to determine human safety. Nor are they ethical.
To prove safety we put our products through a rigorous series of tests. Among these are:
- 30-Day HRIPT (Human Repeat Insult Patch Test) to determine irritancy and allergy potential of a leave-on product. Results are reviewed and signed by a board certified dermatologist.
- 14-Day Clinical Evaluation of Ophthalmologic Safety for all products used around the eye. Products are tested for safe use around the eye and for safe use by contact lens wearers. Results are reviewed and signed by a board certified ophthalmologist.
Everything you need for dramatic age correction is included in 24/7 Barrier Repair Cream and 8-in-1 BioSerum, both applied twice a day; and 2-Minute Reveal Masque, applied 1-2 times a week. When used together as directed, within 6 weeks our clinical studies show significant improvement in up to 16 signs of aging:
- Revives Youthful Firmness
- Brightens Age Spots
- Defines Contours
- Smoothes Lines
- Diminishes Wrinkles
- Unclogs & Minimizes Pores
- Comforts Sensitivity
- Evens Skin Tone
- Corrects Surface Imperfections
- Revives Clarity
- Replenishes Moisture
- Repairs Dryness
- Refines Texture
- Renews Softness
- Revitalizes Dullness
- Calms Redness
Aging skin is a global condition that occurs in any skin type (dry, oily, normal, combination). Since all aging skin has the same basic needs, we’ve formulated each product for use by all skin types, thereby eliminating the need to analyze your skin. If your skin is aging, you can use our products.